产品概述:
产品参数
外观:可溶于 DMSO,DMF 或 EtOH 的红色固体
Ex/Em:548/573 nm (MeOH)
CAS 号:115532-50-8
分子式:C25H25ClN2O7
分子量:500.9
分子结构图:
储存条件
-20℃ 避光保存,有效期见外包装。
产品介绍
TMRM(四甲基罗丹明甲酯)是一种阳离子细胞渗透型荧光染料,易与活跃的线粒体螯合,是可用能斯特方程定量测量膜电位的优选染料。染料不会在细胞膜中形成聚集体,并且与膜蛋白具有最小的相互作用。因此,根据能斯特方程,染料的跨膜分布与膜电位直接相关。
注意事项
1. 荧光染料均存在淬灭问题,请尽量注意避光,以减缓荧光淬灭。
2. 为了您的安全和健康,请穿实验服并戴一次性手套操作。
使用本产品的文献:
1. Transcriptional characteristics and functional validation of three monocyte subsets during aging.
Chen Wang, Yating Cheng , Boyu Li , Xueping Qiu , Hui Hu , Xiaokang Zhang , Zhibing Lu and Fang Zheng
Wang et al. Immunity & Ageing (2023) 20:50
参考文献
1.Tetramethyl Rhodamine Methyl Ester (TMRM) is Suitable for Cytofluorometric Measurements of Mitochondrial Membrane Potential in Cells Treated with Digitonin应用方向:检测线粒体膜电位
2.Loss of Autophagy in Erythroid Cells Leads to Defective Removal of Mitochondria and Severe Anemia in Vivo
应用方向:损伤线粒体损伤检测,监测膜电位改变导致的细胞死亡
3.Relationship between Cell Cycle Changes and Variations of the Mitochondrial Membrane Potential Induced by Etoposide
应用方向:检测药物诱导的DeltaPsi(mt)变化
4.Mitochondrial and Plasma Membrane Potential of Cultured Cerebellar Neurons during Glutamate-Induced Necrosis, Apoptosis, and Tolerance
应用方向:delta-psi(m)的超极化研究
5.TOXI-SIM-A Simulation Tool for the Analysis of Mitochondrial and Plasma Membrane Potentials
应用方向:表征线粒体功能的变化